PUDP

Across TCGA cell cohorts, PUDP RNA expression is significantly associated with the go_rna of many other GO terms, with 2,685 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PUDP-associated GO terms across cancer lineages are Growth hormone secretion, DNA strand elongation, and Lagging strand elongation. Each is linked with PUDP in more than 7 cancer types. Because this analysis shows association rather than direction, both PUDP-to-partner and partner-to-PUDP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Growth hormone secretion grouped by PUDP-low versus PUDP-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PUDP→partner) and Y-score (partner→PUDP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Growth hormone secretion →	+0.125	+0.840	<.001	<.001	3	8
BLOOD_Lymphoma	DNA strand elongation →	+0.095	+1.174	<.001	<.001	3	6
BLOOD_Lymphoma	Lagging strand elongation →	+0.105	+1.084	.001	.001	3	6
OVARY	Cellular response to insulin-like growth factor stimulus →	+0.109	+0.840	.001	.002	3	6
BLOOD_Myeloma	Purine-containing compound biosynthetic process →	+0.054	+2.100	.004	.005	3	5
BLOOD_Leukemia	Excitatory synapse assembly →	-0.081	-0.604	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,685 associations by consensus.

Growth hormone secretion by PUDP expression — BLOOD_Leukemia

Explore this box plot interactively →