PTX4

Across TCGA cell cohorts, PTX4 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,440 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PTX4-associated GO terms across cancer lineages are IMP salvage, Membrane raft localization, and Calcium-independent cell-matrix adhesion. Each is linked with PTX4 in more than 5 cancer types. Because this analysis shows association rather than direction, both PTX4-to-partner and partner-to-PTX4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IMP salvage grouped by PTX4-low versus PTX4-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PTX4→partner) and Y-score (partner→PTX4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	IMP salvage →	+0.145	+0.045	<.001	.003	3	6
SKIN	Membrane raft localization →	-0.106	-0.037	.005	.009	3	6
SOFT_TISSUE	Calcium-independent cell-matrix adhesion →	+0.162	+0.126	<.001	.006	3	5
SOFT_TISSUE	Pre-mRNA catabolic process →	+0.108	+0.098	.001	.006	3	5
LUNG_NSCLC_LUSC	Transcription initiation at RNA polymerase I promoter →	+0.095	+0.062	.001	.003	3	5
LARGE_INTESTINE	Regulation of protein processing →	-0.065	-0.062	.006	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,440 associations by consensus.

IMP salvage by PTX4 expression — LUNG_NSCLC_LUAD

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