PTTG2

Across TCGA patient cohorts, PTTG2 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. LIHC shows the largest number of these associations.

The most reproducible PTTG2-associated genes across cancer lineages are CD4+ Tem and Smooth muscle. Each is linked with PTTG2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PTTG2-to-partner and partner-to-PTTG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD4+ Tem grouped by PTTG2-low versus PTTG2-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTTG2→partner) and Y-score (partner→PTTG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	CD4+ Tem →	+0.092	+4.283	<.001	.023	3	1
SKCM	Smooth muscle →	+0.167	+3.006	.008	.020	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CD4+ Tem by PTTG2 expression — LIHC

Explore this box plot interactively →