Across TCGA patient cohorts, PTRHD1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,600 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PTRHD1-associated genes across cancer lineages are RAB5B, MIR17HG, and EIF3B. Each is linked with PTRHD1 in more than 3 cancer types. Because this analysis shows association rather than direction, both PTRHD1-to-partner and partner-to-PTRHD1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTRHD1→partner) and Y-score (partner→PTRHD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RAB5B →	+0.467	+0.389	<.001	<.001	3	4
UCEC	MIR17HG →	-0.921	-0.532	<.001	<.001	3	4
BRCA	EIF3B →	-0.329	-0.263	.003	.009	3	3
LSCC	CEP70 →	+0.553	+0.253	<.001	<.001	3	3
LSCC	FBXO21 →	+0.508	+0.276	<.001	.001	3	3
OV	HADHB →	+0.542	+0.374	.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,600 associations by consensus.

Exploration

PTRHD1 survival (RNA) · tumor vs normal (RNA) · all PTRHD1 data types