Across TCGA patient cohorts, PTRHD1 protein abundance is significantly associated with the protein abundance of many other proteins, with 20,196 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PTRHD1-associated proteins across cancer lineages are RPS3_T242, KDM2A_S692, and PHF2_S882. Each is linked with PTRHD1 in more than 5 cancer types. Because this analysis shows association rather than direction, both PTRHD1-to-partner and partner-to-PTRHD1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PTRHD1→partner) and Y-score (partner→PTRHD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	RPS3_T242 →	+0.468	+0.451	<.001	<.001	3	6
UCEC	KDM2A_S692 →	-0.521	-0.607	<.001	<.001	3	6
LUAD	PHF2_S882 →	-0.826	-0.313	<.001	<.001	3	6
BRCA	HNRNPA3_S116 →	+1.297	+0.525	<.001	<.001	3	6
UCEC	RNF113A_S253 →	-0.545	-0.436	<.001	<.001	3	5
UCEC	TOP2B_S1375 →	-0.787	-0.543	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,196 associations by consensus.

Exploration

PTRHD1 survival (RNA) · tumor vs normal (RNA) · all PTRHD1 data types