Across TCGA patient cohorts, PTRHD1 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible PTRHD1-associated genes across cancer lineages are SDR42E1P4, GEMIN2P2, and NMBR-AS1. Each is linked with PTRHD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PTRHD1-to-partner and partner-to-PTRHD1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTRHD1→partner) and Y-score (partner→PTRHD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SDR42E1P4 →	+0.199	+8.066	<.001	.007	3	1
SKCM	GEMIN2P2 →	+0.085	+4.993	<.001	.002	3	1
SKCM	NMBR-AS1 →	+0.159	+4.513	<.001	.009	3	1
SKCM	RNGTTP1 →	+0.114	+4.440	<.001	.006	3	1
SKCM	RNU6-764P →	+0.324	+4.594	<.001	.008	3	1
SKCM	RNU6-344P →	+0.299	+5.199	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Exploration

PTRHD1 survival (RNA) · tumor vs normal (RNA) · all PTRHD1 data types