Across TCGA patient cohorts, PTRH1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,737 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PTRH1-associated genes across cancer lineages are LRRN1, DPYSL2, and CXCR4. Each is linked with PTRH1 in more than 2 cancer types. Because this analysis shows association rather than direction, both PTRH1-to-partner and partner-to-PTRH1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTRH1→partner) and Y-score (partner→PTRH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LRRN1 →	-1.170	-0.281	.002	<.001	3	3
LSCC	DPYSL2 →	-0.576	-0.251	.002	.004	3	3
COAD	CXCR4 →	-0.785	-0.274	<.001	.001	3	3
LSCC	CCNJL →	-0.734	-0.256	<.001	.002	3	3
OV	CPAMD8 →	-1.066	-0.304	<.001	.005	3	3
OV	S1PR2 →	-0.914	-0.506	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,737 associations by consensus.

Exploration

PTRH1 survival (RNA) · tumor vs normal (RNA) · all PTRH1 data types