Across TCGA patient cohorts, PTRH1 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. COAD shows the largest number of these associations.

The most reproducible PTRH1-associated genes across cancer lineages are CD8+ T-cells, CD8+ Tcm, and Monocytes. Each is linked with PTRH1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PTRH1-to-partner and partner-to-PTRH1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTRH1→partner) and Y-score (partner→PTRH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CD8+ T-cells →	+0.089	+6.142	<.001	.027	3	1
COAD	CD8+ Tcm →	+0.151	+5.917	<.001	.032	3	1
COAD	Monocytes →	+0.072	+6.734	<.001	.018	3	1
COAD	CD4+ naive T-cells →	+0.047	+6.142	<.001	.027	3	1
BRCA	CD4+ Tem →	+0.008	+6.234	.024	.026	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

PTRH1 survival (RNA) · tumor vs normal (RNA) · all PTRH1 data types