Across TCGA patient cohorts, PTPRT RNA expression is significantly associated with the protein abundance of many other proteins, with 19,195 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PTPRT-associated proteins across cancer lineages are HDGFL3, MAP1A, and APPL1. Each is linked with PTPRT in more than 6 cancer types. Because this analysis shows association rather than direction, both PTPRT-to-partner and partner-to-PTPRT results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PTPRT→partner) and Y-score (partner→PTPRT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HDGFL3 →	+0.546	+2.005	<.001	<.001	3	7
GBM	MAP1A →	+0.480	+1.801	<.001	<.001	3	5
BRCA	APPL1 →	+0.219	+1.492	<.001	<.001	3	5
HNSC	USP15 →	-0.253	-0.639	<.001	.001	3	5
BRCA	RERG →	+0.647	+1.581	<.001	<.001	3	5
BRCA	DDX21_S121 →	-0.677	-1.419	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,195 associations by consensus.

Exploration

PTPRT survival (RNA) · tumor vs normal (RNA) · all PTPRT data types