Across TCGA patient cohorts, PTPRT protein abundance is significantly associated with the RNA expression of many other genes, with 2,376 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PTPRT-associated genes across cancer lineages are TFF2, PRODH, and SOX10. Each is linked with PTPRT in more than 1 cancer types. Because this analysis shows association rather than direction, both PTPRT-to-partner and partner-to-PTPRT results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTPRT→partner) and Y-score (partner→PTPRT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TFF2 →	+1.560	+1.101	<.001	.008	3	1
GBM	PRODH →	+0.980	+0.350	<.001	.001	3	1
GBM	SOX10 →	+1.409	+0.308	<.001	<.001	3	1
GBM	SEPTIN3 →	+0.753	+0.315	.002	<.001	3	1
GBM	RASL10A →	+0.675	+0.328	<.001	<.001	3	1
GBM	NEFH →	+0.906	+0.312	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,376 associations by consensus.

Exploration

PTPRT survival (RNA) · tumor vs normal (RNA) · all PTPRT data types