PTPRN2-AS1

Across TCGA pan-cancer cohorts, PTPRN2-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated PTPRN2-AS1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher PTPRN2-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated PTPRN2-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and SKCM show a favorable association.

HNSC, SKCM, and LGG are the cancer types where PTPRN2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	II,III,IV	0.741	0.627	<.001	130	view →
SKCM	OS	Median	All	0.400	0.270	<.001	83	view →
LGG	OS	Median	All	0.350	0.546	<.001	49	view →
UVM	DFS	Tertile	All	0.395	0.788	.001	32	view →
CESC	DFS	Tertile	II,III,IV	0.903	0.692	.005	30	view →
STAD	OS	Median	III,IV	0.451	0.206	.006	27	view →
KIRC	DFS	Tertile	IV	0.458	0.722	.003	23	view →
UCEC	DFS	Tertile	All	0.702	0.570	.007	22	view →
PAAD	OS	Median	II,III,IV	0.664	0.507	.007	20	view →
ESCA	DFS	Median	All	0.484	0.922	.005	18	view →
DLBC	OS	Tertile	All	1.000	0.443	.011	17	view →
GBM	DFS	Median	All	0.153	0.248	.004	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

PTPRN2-AS1–HNSC (DFS)

Open the HNSC breakdown →