PTPRK

Across TCGA cell cohorts, PTPRK RNA expression is significantly associated with the go_rna of many other GO terms, with 5,635 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PTPRK-associated GO terms across cancer lineages are Cell-substrate junction organization, Endosome organization, and Vacuolar transport. Each is linked with PTPRK in more than 13 cancer types. Because this analysis shows association rather than direction, both PTPRK-to-partner and partner-to-PTPRK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell-substrate junction organization grouped by PTPRK-low versus PTPRK-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PTPRK→partner) and Y-score (partner→PTPRK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Cell-substrate junction organization →	+0.140	+1.085	.007	.002	2	14
SOFT_TISSUE	Endosome organization →	+0.076	+2.203	<.001	<.001	3	13
SOFT_TISSUE	Vacuolar transport →	+0.050	+2.238	<.001	.001	2	13
CNS	Epiboly →	+0.146	+0.970	<.001	.003	3	12
BONE	Viral process →	+0.107	+1.285	<.001	<.001	3	12
BONE	Positive regulation of protein localization to plasma membrane →	+0.172	+1.309	<.001	.009	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,635 associations by consensus.

Cell-substrate junction organization by PTPRK expression — URINARY_TRACT

Explore this box plot interactively →