PTPRJ

Across TCGA patient cohorts, PTPRJ protein abundance is significantly associated with the RNA expression of many other genes, with 16,651 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PTPRJ-associated genes across cancer lineages are LCP2, BCL2A1, and CEACAM3. Each is linked with PTPRJ in more than 9 cancer types. Because this analysis shows association rather than direction, both PTPRJ-to-partner and partner-to-PTPRJ results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTPRJ versus LCP2 in COAD, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTPRJ→partner) and Y-score (partner→PTPRJ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	LCP2 →	+1.115	+0.601	<.001	<.001	3	10
OV	BCL2A1 →	+1.347	+0.381	<.001	<.001	3	9
PDAC	CEACAM3 →	+0.796	+0.549	<.001	<.001	3	9
COAD	PLEK →	+1.010	+0.390	.001	.005	3	9
OV	CCR1 →	+1.315	+0.435	<.001	<.001	3	9
OV	CD300A →	+1.095	+0.320	<.001	.003	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,651 associations by consensus.

PTPRJ vs LCP2 — COAD

Explore this scatter interactively →