PTPRJ

Across TCGA cell cohorts, PTPRJ mutation is significantly associated with the RNA expression of many other genes, with 35 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PTPRJ-associated genes across cancer lineages are FABP9, TECTB, and IFNW1. Each is linked with PTPRJ in more than 1 cancer types. Because this analysis shows association rather than direction, both PTPRJ-to-partner and partner-to-PTPRJ results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FABP9 grouped by PTPRJ-low versus PTPRJ-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTPRJ→partner) and Y-score (partner→PTPRJ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	FABP9 →	+0.055	+4.614	<.001	.004	3	2
PANCREAS	TECTB →	+0.942	+4.011	<.001	.009	3	1
SOFT_TISSUE	IFNW1 →	+0.012	+4.930	.003	.008	3	1
SOFT_TISSUE	MDFIC2 →	+0.276	+4.930	<.001	.008	3	1
LARGE_INTESTINE	CPO →	+0.124	+3.514	<.001	.007	3	1
LARGE_INTESTINE	SLN →	+0.136	+3.706	.004	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

FABP9 by PTPRJ expression — PANCREAS

Explore this box plot interactively →