PTPRJ-AS1

Across TCGA pan-cancer cohorts, PTPRJ-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated PTPRJ-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher PTPRJ-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PTPRJ-AS1 expression acts as an unfavorable survival marker, although some lineages such as STAD and SKCM show a favorable association.

ACC, KIRC, and MESO are the cancer types where PTPRJ-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	All	0.543	0.894	<.001	99	view →
KIRC	OS	Median	All	0.763	0.843	.002	56	view →
MESO	OS	Quartile	IV	0.129	0.701	<.001	36	view →
STAD	OS	Tertile	II,III,IV	0.567	0.374	.011	27	view →
LGG	DFS	Tertile	All	0.700	0.878	<.001	24	view →
UVM	DFS	Quartile	III,IV	0.353	0.816	.004	22	view →
HNSC	OS	Tertile	IV	0.305	0.559	.012	20	view →
BLCA	OS	Quartile	All	0.513	0.728	.005	16	view →
PAAD	DFS	Tertile	III,IV	0.496	0.853	.038	15	view →
SKCM	OS	Median	II,III,IV	0.605	0.233	.007	13	view →
COAD	OS	Tertile	III,IV	0.742	0.441	.024	11	view →
ESCA	OS	Quartile	All	0.617	0.782	.032	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

PTPRJ-AS1–ACC (OS)

Open the ACC breakdown →