PTPRG

Across TCGA patient cohorts, PTPRG protein abundance is significantly associated with the RNA expression of many other genes, with 12,465 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PTPRG-associated genes across cancer lineages are ID2B, PTPRG-AS1, and RNU2-10P. Each is linked with PTPRG in more than 5 cancer types. Because this analysis shows association rather than direction, both PTPRG-to-partner and partner-to-PTPRG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTPRG versus ID2B in CCRCC, with a Pearson correlation of 0.73.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTPRG→partner) and Y-score (partner→PTPRG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	ID2B →	+1.140	+0.414	<.001	<.001	3	6
CCRCC	PTPRG-AS1 →	+0.814	+0.434	<.001	<.001	3	6
CCRCC	RNU2-10P →	+1.069	+0.396	<.001	<.001	3	6
BRCA	PEAK1 →	+0.547	+0.360	<.001	<.001	3	5
BRCA	TCF4 →	+0.818	+0.468	<.001	<.001	3	5
BRCA	PMP22 →	+0.763	+0.322	.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,465 associations by consensus.

PTPRG vs ID2B — CCRCC

Explore this scatter interactively →