PTPRCAP

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, PTPRCAP Mutation is linked to patient survival in 5 of 34 cancer types, making it the most broadly survival-associated PTPRCAP data layer compared with 1 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher PTPRCAP Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated PTPRCAP expression acts as an unfavorable survival marker.

STAD, LUAD, and COAD are the cancer types where PTPRCAP Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
STADOSMedianAll0.1640.689<.00136view →
LUADDFSMedianAll0.0770.768<.00112view →
COADOSMedianAll0.0010.871<.00112view →
SARCDFSMedianAll0.1210.611.0416view →
PRADDFSMedianAll0.0850.774<.0016view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration