PTPRCAP

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, PTPRCAP mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated PTPRCAP data layer compared with 1 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher PTPRCAP mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated PTPRCAP expression acts as an unfavorable survival marker, although some lineages such as LUAD and CCRCC show a favorable association.

LUAD, CCRCC, and HNSC are the cancer types where PTPRCAP mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUADDFSTertileAll0.8120.523.00314view →
CCRCCOSTertileII,III,IV1.0000.708.0039view →
HNSCDFSTertileII,III,IV0.9331.000.0282view →
LSCCOSTertileII,III,IV0.5630.845.0441view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration