Across TCGA patient cohorts, PTPRCAP mutation is significantly associated with the RNA expression of many other genes, with 51 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PTPRCAP-associated genes across cancer lineages are RNU6-340P, OFD1P11Y, and LSP1P3. Each is linked with PTPRCAP in more than 1 cancer types. Because this analysis shows association rather than direction, both PTPRCAP-to-partner and partner-to-PTPRCAP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTPRCAP→partner) and Y-score (partner→PTPRCAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-340P →	+0.363	+7.741	<.001	.009	3	1
SKCM	OFD1P11Y →	+0.039	+7.816	<.001	.008	3	1
UCEC	LSP1P3 →	+0.411	+3.063	<.001	.008	3	1
UCEC	IGKV2-40 →	+0.510	+3.386	<.001	.008	3	1
LUAD	OR5M5P →	+0.118	+5.631	<.001	.004	3	1
LUAD	FAM224A →	+0.024	+5.099	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 51 associations by consensus.

Exploration

PTPRCAP survival (RNA) · tumor vs normal (RNA) · all PTPRCAP data types