PTPRC

Across TCGA patient cohorts, PTPRC RNA expression is significantly associated with the protein abundance of many other proteins, with 22,839 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PTPRC-associated proteins across cancer lineages are RASAL3, WAS, and WDFY4. Each is linked with PTPRC in more than 9 cancer types. Because this analysis shows association rather than direction, both PTPRC-to-partner and partner-to-PTPRC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTPRC versus RASAL3 in LSCC, with a Pearson correlation of 0.85.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PTPRC→partner) and Y-score (partner→PTPRC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RASAL3 →	+0.618	+1.138	<.001	<.001	3	10
GBM	WAS →	+0.780	+1.290	<.001	<.001	3	10
LSCC	WDFY4 →	+0.664	+1.117	<.001	<.001	3	10
OV	WIPF1 →	+0.513	+1.362	<.001	<.001	3	10
LSCC	ZAP70 →	+0.828	+1.091	<.001	<.001	3	10
HNSC	RCSD1 →	+0.735	+1.160	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,839 associations by consensus.

PTPRC vs RASAL3 — LSCC

Explore this scatter interactively →