PTPRA

Across TCGA patient cohorts, PTPRA protein abundance is significantly associated with the RNA expression of many other genes, with 6,407 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PTPRA-associated genes across cancer lineages are CDS2, CENPB, and PCED1A. Each is linked with PTPRA in more than 4 cancer types. Because this analysis shows association rather than direction, both PTPRA-to-partner and partner-to-PTPRA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTPRA versus CDS2 in COAD, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTPRA→partner) and Y-score (partner→PTPRA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CDS2 →	+0.640	+0.303	<.001	<.001	3	5
OV	CENPB →	+0.743	+0.320	<.001	.005	3	5
OV	PCED1A →	+0.732	+0.315	.005	.003	3	5
OV	ATRN →	+0.750	+0.293	<.001	.008	3	5
GBM	TBC1D20 →	+0.334	+0.313	<.001	<.001	3	4
OV	IDH3B →	+0.650	+0.353	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,407 associations by consensus.

PTPRA vs CDS2 — COAD

Explore this scatter interactively →