PTPRA

Across TCGA patient cohorts, PTPRA mutation is significantly associated with the RNA expression of many other genes, with 4,851 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PTPRA-associated genes across cancer lineages are LINC00561, RACGAP1, and CHRNA5. Each is linked with PTPRA in more than 2 cancer types. Because this analysis shows association rather than direction, both PTPRA-to-partner and partner-to-PTPRA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00561 grouped by PTPRA-low versus PTPRA-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTPRA→partner) and Y-score (partner→PTPRA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	LINC00561 →	+0.008	+4.149	.003	.009	3	3
UCEC	RACGAP1 →	+0.575	+1.551	<.001	<.001	3	3
COAD	CHRNA5 →	+0.827	+3.210	<.001	.009	3	3
COAD	FAM210A →	+0.701	+3.209	<.001	.009	3	3
UCEC	CCSAP →	+0.607	+1.743	<.001	<.001	3	3
UCEC	VPS37A →	+0.616	+2.140	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,851 associations by consensus.

LINC00561 by PTPRA expression — LIHC

Explore this box plot interactively →