PTPN9

Across TCGA patient cohorts, PTPN9 RNA expression is significantly associated with the RNA expression of many other genes, with 20,612 significant associations in total. ACC shows the largest number of these associations.

The most reproducible PTPN9-associated genes across cancer lineages are RALGAPB, AKAP13, and BPTF. Each is linked with PTPN9 in more than 33 cancer types. Because this analysis shows association rather than direction, both PTPN9-to-partner and partner-to-PTPN9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTPN9 versus RALGAPB in ACC, with a Pearson correlation of 0.66.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTPN9→partner) and Y-score (partner→PTPN9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	RALGAPB →	+1.190	+1.531	<.001	<.001	3	34
SCLC	AKAP13 →	+1.329	+0.463	<.001	<.001	3	34
DLBC	BPTF →	+1.381	+0.823	<.001	<.001	3	34
THYM	PEAK1 →	+1.394	+0.981	<.001	<.001	3	34
DLBC	CHD2 →	+1.271	+0.749	<.001	<.001	3	34
UVM	DENND4A →	+1.289	+0.897	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,612 associations by consensus.

PTPN9 vs RALGAPB — ACC

Explore this scatter interactively →