PTPN7

Across TCGA patient cohorts, PTPN7 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,014 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PTPN7-associated proteins across cancer lineages are MYO1F, MYO1G, and ARHGAP15_S64. Each is linked with PTPN7 in more than 9 cancer types. Because this analysis shows association rather than direction, both PTPN7-to-partner and partner-to-PTPN7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTPN7 versus MYO1F in GBM, with a Pearson correlation of 0.69.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PTPN7→partner) and Y-score (partner→PTPN7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MYO1F →	+0.635	+0.691	<.001	<.001	3	10
BRCA	MYO1G →	+0.672	+1.246	<.001	<.001	3	10
BRCA	ARHGAP15_S64 →	+1.103	+1.255	<.001	<.001	3	10
OV	ARHGAP25 →	+0.792	+0.824	.002	.004	3	10
LSCC	ARHGAP45 →	+0.604	+0.921	<.001	<.001	3	10
OV	WIPF1 →	+0.478	+0.847	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,014 associations by consensus.

PTPN7 vs MYO1F — GBM

Explore this scatter interactively →