Across TCGA patient cohorts, PTPN20 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,041 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PTPN20-associated proteins across cancer lineages are SURF4, CDC14A_S484, and POLR1B. Each is linked with PTPN20 in more than 2 cancer types. Because this analysis shows association rather than direction, both PTPN20-to-partner and partner-to-PTPN20 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PTPN20→partner) and Y-score (partner→PTPN20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SURF4 →	-0.338	-0.600	.001	<.001	3	3
OV	CDC14A_S484 →	+0.635	+1.047	.006	.006	3	3
GBM	POLR1B →	-0.217	-0.342	.002	.003	3	3
UCEC	VWA5B2 →	+0.690	+0.686	<.001	<.001	3	3
GBM	PRC1 →	-0.532	-0.465	.002	.003	3	2
HNSC	TP53BP1_S660 →	+0.470	+0.738	.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,041 associations by consensus.

Exploration

PTPN20 survival (RNA) · tumor vs normal (RNA) · all PTPN20 data types