PTPN20

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PTPN20 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,658 significant associations in total. OESOPHAGUS shows the largest number of these associations.

The most reproducible PTPN20-associated GO terms across cancer lineages are Regulation of syncytium formation by plasma membrane fusion, Regulation of myoblast fusion, and Negative regulation of myoblast fusion. Each is linked with PTPN20 in more than 8 cancer types. Because this analysis shows association rather than direction, both PTPN20-to-partner and partner-to-PTPN20 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PTPN20→partner) and Y-score (partner→PTPN20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHRegulation of syncytium formation by plasma membrane fusion →+0.131+1.944<.001<.00139
STOMACHRegulation of myoblast fusion →+0.123+1.604<.001<.00138
STOMACHNegative regulation of myoblast fusion →+0.131+1.672<.001<.00137
STOMACHNegative regulation of syncytium formation by plasma membrane fusion →+0.129+1.672<.001<.00137
OESOPHAGUSATP synthesis coupled electron transport →+0.113+1.528<.001.00136
OESOPHAGUSMitochondrial ATP synthesis coupled electron transport →+0.113+1.528<.001.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,658 associations by consensus.

Exploration