PTPN13

Across TCGA pan-cancer cohorts, PTPN13 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated PTPN13 data layer compared with 22 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher PTPN13 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated PTPN13 expression acts as an unfavorable survival marker, although some lineages such as LUAD and CCRCC show a favorable association.

LUAD, CCRCC, and HNSC are the cancer types where PTPN13 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	II,III,IV	0.821	0.392	<.001	12	view →
CCRCC	OS	Median	All	1.000	0.687	.018	8	view →
HNSC	OS	Quartile	All	1.000	0.920	.022	6	view →
UCEC	OS	Tertile	III,IV	0.315	1.000	.042	4	view →
GBM	DFS	Median	All	0.227	0.412	.041	4	view →
LSCC	DFS	Median	II,III,IV	0.485	1.000	.006	3	view →
PDAC	OS	Median	II,III,IV	0.439	0.606	.017	3	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

PTPN13–LUAD (OS)

Open the LUAD breakdown →