PTPN1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PTPN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,504 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PTPN1-associated GO terms across cancer lineages are Insulin receptor recycling, Response to oscillatory fluid shear stress, and Cellular response to oscillatory fluid shear stress. Each is linked with PTPN1 in more than 18 cancer types. Because this analysis shows association rather than direction, both PTPN1-to-partner and partner-to-PTPN1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PTPN1→partner) and Y-score (partner→PTPN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHInsulin receptor recycling →+0.245+1.225<.001.001319
BLOOD_LeukemiaResponse to oscillatory fluid shear stress →+0.175+0.958<.001<.001319
BLOOD_LeukemiaCellular response to oscillatory fluid shear stress →+0.175+0.958<.001<.001319
BLOOD_LeukemiaVascular endothelial cell response to oscillatory fluid shear stress →+0.175+0.958<.001<.001319
STOMACHIRE1-mediated unfolded protein response →+0.179+1.173<.001<.001317
LIVERCellular response to platelet-derived growth factor stimulus →+0.147+0.696.008.003314
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,504 associations by consensus.

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