PTPMT1

Across TCGA cell cohorts, PTPMT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,590 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PTPMT1-associated GO terms across cancer lineages are CAAX-box protein processing, Cellular detoxification of methylglyoxal, and Positive regulation of type B pancreatic cell development. Each is linked with PTPMT1 in more than 8 cancer types. Because this analysis shows association rather than direction, both PTPMT1-to-partner and partner-to-PTPMT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CAAX-box protein processing grouped by PTPMT1-low versus PTPMT1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PTPMT1→partner) and Y-score (partner→PTPMT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	CAAX-box protein processing →	+0.144	+1.337	.002	.005	3	9
CNS	Cellular detoxification of methylglyoxal →	+0.086	+0.338	<.001	.004	3	7
OVARY	Positive regulation of type B pancreatic cell development →	+0.185	+0.676	<.001	.004	3	7
LARGE_INTESTINE	Pyruvate decarboxylation to acetyl-CoA →	+0.142	+0.820	<.001	<.001	3	7
PANCREAS	Thymidine biosynthetic process →	+0.125	+0.517	.002	.004	2	8
PANCREAS	2'-deoxyribonucleoside biosynthetic process →	+0.125	+0.517	.002	.004	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,590 associations by consensus.

CAAX-box protein processing by PTPMT1 expression — BONE

Explore this box plot interactively →