PTPDC1

Across TCGA patient cohorts, PTPDC1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,442 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PTPDC1-associated genes across cancer lineages are ALG3, GPIHBP1, and PDK4. Each is linked with PTPDC1 in more than 2 cancer types. Because this analysis shows association rather than direction, both PTPDC1-to-partner and partner-to-PTPDC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTPDC1 versus ALG3 in LSCC, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTPDC1→partner) and Y-score (partner→PTPDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ALG3 →	-0.850	-0.252	<.001	.004	3	3
BRCA	GPIHBP1 →	+1.121	+0.483	<.001	<.001	3	3
HNSC	PDK4 →	+1.971	+0.974	<.001	<.001	3	3
BRCA	ABCC9 →	+0.984	+0.491	<.001	.002	3	3
LSCC	SLC25A11 →	-0.496	-0.448	.007	<.001	3	2
CCRCC	TDP2 →	-0.777	-0.805	.003	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,442 associations by consensus.

PTPDC1 vs ALG3 — LSCC

Explore this scatter interactively →