PTPDC1

Across TCGA cell cohorts, PTPDC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,273 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PTPDC1-associated GO terms across cancer lineages are RNA export from nucleus, Epigenetic regulation of gene expression, and Signal transduction in response to DNA damage. Each is linked with PTPDC1 in more than 13 cancer types. Because this analysis shows association rather than direction, both PTPDC1-to-partner and partner-to-PTPDC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA export from nucleus grouped by PTPDC1-low versus PTPDC1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PTPDC1→partner) and Y-score (partner→PTPDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	RNA export from nucleus →	+0.120	+0.974	<.001	<.001	3	14
SOFT_TISSUE	Epigenetic regulation of gene expression →	+0.059	+1.025	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Signal transduction in response to DNA damage →	+0.071	+0.851	<.001	<.001	3	13
OESOPHAGUS	Regulation of RNA splicing →	+0.090	+1.316	.005	.004	3	13
LUNG_NSCLC_LUSC	Nucleic acid transport →	+0.108	+0.902	<.001	<.001	3	13
LUNG_NSCLC_LUSC	RNA transport →	+0.108	+0.902	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,273 associations by consensus.

RNA export from nucleus by PTPDC1 expression — SOFT_TISSUE

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