Across TCGA patient cohorts, PTP4A3 protein abundance is significantly associated with the RNA expression of many other genes, with 8,363 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PTP4A3-associated genes across cancer lineages are TXNL4B, CTSS, and PLEKHM1. Each is linked with PTP4A3 in more than 2 cancer types. Because this analysis shows association rather than direction, both PTP4A3-to-partner and partner-to-PTP4A3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTP4A3→partner) and Y-score (partner→PTP4A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TXNL4B →	-0.416	-0.246	<.001	<.001	3	3
OV	CTSS →	-1.081	-0.811	<.001	.008	3	3
OV	PLEKHM1 →	-0.508	-0.688	.001	.002	3	3
COAD	GDAP1 →	+0.823	+1.096	.008	.005	3	3
GBM	NTRK3 →	+0.872	+0.463	.007	.004	3	3
GBM	BRSK2 →	+0.836	+0.341	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,363 associations by consensus.

Exploration

PTP4A3 survival (RNA) · tumor vs normal (RNA) · all PTP4A3 data types