Across TCGA patient cohorts, PTP4A3 protein abundance is significantly associated with the protein abundance of many other proteins, with 10,926 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PTP4A3-associated proteins across cancer lineages are MLPH, CALCOCO2, and RCSD1_S179. Each is linked with PTP4A3 in more than 2 cancer types. Because this analysis shows association rather than direction, both PTP4A3-to-partner and partner-to-PTP4A3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PTP4A3→partner) and Y-score (partner→PTP4A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MLPH →	-0.773	-0.601	.004	<.001	3	3
GBM	CALCOCO2 →	-0.290	-0.538	<.001	<.001	3	3
LSCC	RCSD1_S179 →	+0.639	+0.300	<.001	<.001	3	2
BRCA	RHBDD2 →	-0.593	-0.359	.002	.001	3	2
BRCA	RNF185 →	-0.512	-0.342	<.001	.001	3	2
LSCC	SCYL2_T708 →	-1.058	-0.321	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,926 associations by consensus.

Exploration

PTP4A3 survival (RNA) · tumor vs normal (RNA) · all PTP4A3 data types