Across TCGA patient cohorts, PTP4A3 mutation is significantly associated with the RNA expression of many other genes, with 2,073 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PTP4A3-associated genes across cancer lineages are CD24P1, MTND1P33, and RN7SL713P. Each is linked with PTP4A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both PTP4A3-to-partner and partner-to-PTP4A3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTP4A3→partner) and Y-score (partner→PTP4A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CD24P1 →	+0.262	+5.357	.002	.006	3	2
SKCM	MTND1P33 →	+0.040	+5.039	<.001	.003	3	2
UCEC	RN7SL713P →	+0.069	+2.787	.009	.003	3	2
LIHC	DNM1P41 →	+0.017	+4.733	<.001	.003	3	1
UCEC	HSPE1-MOB4 →	+0.162	+2.214	<.001	.003	3	1
UCEC	SRXN1 →	+0.680	+2.721	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,073 associations by consensus.

Exploration

PTP4A3 survival (RNA) · tumor vs normal (RNA) · all PTP4A3 data types