PTP4A1P3

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, PTP4A1P3 RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated PTP4A1P3 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher PTP4A1P3 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PTP4A1P3 expression acts as an unfavorable survival marker, although some lineages such as BRCA and LAML show a favorable association.

MESO, ACC, and BRCA are the cancer types where PTP4A1P3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
MESOOSTertileIV0.0360.602<.00172view →
ACCOSTertileAll0.1450.705.00272view →
BRCADFSTertileIII,IV0.7420.435.03318view →
PCPGDFSTertileAll0.0770.777<.00118view →
THYMOSTertileAll0.3810.879.00312view →
BLCADFSTertileIV0.1780.481.0269view →
STADDFSTertileIV0.1020.412.0199view →
LAMLDFSMedianAll0.6420.494.0388view →
Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

Exploration