PTP4A1P1

Across TCGA pan-cancer cohorts, PTP4A1P1 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated PTP4A1P1 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher PTP4A1P1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PTP4A1P1 expression acts as an unfavorable survival marker, although some lineages such as ACC and ESCA show a favorable association.

KICH, LUSC, and STAD are the cancer types where PTP4A1P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Tertile	All	0.600	0.928	<.001	66	view →
LUSC	DFS	Tertile	III,IV	0.451	0.804	.012	23	view →
STAD	OS	Quartile	II,III,IV	0.436	0.669	.015	19	view →
ACC	DFS	Tertile	IV	0.793	0.152	.026	15	view →
ESCA	DFS	Median	III,IV	0.539	0.318	.016	14	view →
KIRP	DFS	Median	All	0.936	0.641	.014	13	view →
HNSC	OS	Tertile	IV	0.117	0.322	.018	12	view →
LIHC	OS	Tertile	II,III,IV	0.692	0.369	.018	12	view →
THCA	OS	Median	II,III,IV	0.960	0.992	.007	11	view →
LGG	OS	Tertile	All	0.932	0.854	.003	10	view →
LAML	DFS	Quartile	All	0.296	0.498	.044	8	view →
OV	OS	Tertile	All	0.788	0.865	.039	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

PTP4A1P1–KICH (OS)

Open the KICH breakdown →