PTP4A1

Across TCGA patient cohorts, PTP4A1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,852 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PTP4A1-associated genes across cancer lineages are CCN4, POSTN, and GLT8D2. Each is linked with PTP4A1 in more than 5 cancer types. Because this analysis shows association rather than direction, both PTP4A1-to-partner and partner-to-PTP4A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTP4A1 versus CCN4 in GBM, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTP4A1→partner) and Y-score (partner→PTP4A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CCN4 →	-0.975	-0.262	<.001	<.001	3	6
GBM	POSTN →	-2.274	-0.267	<.001	.005	3	6
BRCA	GLT8D2 →	-0.843	-0.326	<.001	<.001	3	5
GBM	COL5A1 →	-1.448	-0.285	.001	.002	3	5
COAD	TLR2 →	-1.067	-0.513	<.001	.001	3	5
GBM	COL6A3 →	-2.056	-0.383	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,852 associations by consensus.

PTP4A1 vs CCN4 — GBM

Explore this scatter interactively →