PTP4A1

Across TCGA cell cohorts, PTP4A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,004 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PTP4A1-associated GO terms across cancer lineages are Spermidine biosynthetic process, Spermine biosynthetic process, and Regulation of calcium ion transmembrane transport via high voltage-gated calcium channel. Each is linked with PTP4A1 in more than 10 cancer types. Because this analysis shows association rather than direction, both PTP4A1-to-partner and partner-to-PTP4A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spermidine biosynthetic process grouped by PTP4A1-low versus PTP4A1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PTP4A1→partner) and Y-score (partner→PTP4A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Spermidine biosynthetic process →	+0.165	+0.865	<.001	<.001	3	11
BREAST	Spermine biosynthetic process →	+0.158	+0.810	<.001	<.001	3	9
OESOPHAGUS	Regulation of calcium ion transmembrane transport via high voltage-gated calcium channel →	+0.087	+1.300	.007	.003	3	8
BLOOD_Lymphoma	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition →	+0.128	+1.369	<.001	<.001	3	8
PANCREAS	Negative regulation of RNA export from nucleus →	+0.119	+0.735	<.001	<.001	3	7
BREAST	7-methylguanosine mRNA capping →	+0.093	+1.105	.002	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,004 associations by consensus.

Spermidine biosynthetic process by PTP4A1 expression — BREAST

Explore this box plot interactively →