PTOV1

Across TCGA patient cohorts, PTOV1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,524 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PTOV1-associated genes across cancer lineages are CPED1, EFEMP1, and GADD45A. Each is linked with PTOV1 in more than 2 cancer types. Because this analysis shows association rather than direction, both PTOV1-to-partner and partner-to-PTOV1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTOV1 versus CPED1 in PDAC, with a Pearson correlation of -0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTOV1→partner) and Y-score (partner→PTOV1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	CPED1 →	-1.275	-0.675	.007	.006	3	2
GBM	EFEMP1 →	-1.052	-0.299	<.001	<.001	3	2
BRCA	GADD45A →	-0.776	-0.465	<.001	.005	3	2
GBM	RGS2 →	-0.964	-0.313	<.001	.001	3	2
UCEC	C12orf65 →	+0.350	+0.363	<.001	<.001	3	2
UCEC	GABARAPL1 →	-0.597	-0.295	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,524 associations by consensus.

PTOV1 vs CPED1 — PDAC

Explore this scatter interactively →