PTOV1

Across TCGA cell cohorts, PTOV1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,106 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PTOV1-associated GO terms across cancer lineages are Symbiont-mediated disruption of host cellular anatomical structure, Symbiont-mediated disruption of host anatomical structure, and Positive regulation of stem cell population maintenance. Each is linked with PTOV1 in more than 14 cancer types. Because this analysis shows association rather than direction, both PTOV1-to-partner and partner-to-PTOV1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Symbiont-mediated disruption of host cellular anatomical structure grouped by PTOV1-low versus PTOV1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PTOV1→partner) and Y-score (partner→PTOV1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Symbiont-mediated disruption of host cellular anatomical structure →	+0.160	+0.778	<.001	<.001	3	15
BREAST	Symbiont-mediated disruption of host anatomical structure →	+0.160	+0.778	<.001	<.001	3	15
LUNG_SCLC	Positive regulation of stem cell population maintenance →	+0.088	+0.833	<.001	<.001	3	13
STOMACH	Regulation of base-excision repair →	+0.175	+1.295	<.001	<.001	3	12
BONE	Regulation of anaphase-promoting complex-dependent catabolic process →	+0.235	+0.996	.003	.001	3	12
BONE	Copper ion export →	-0.235	-1.277	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,106 associations by consensus.

Symbiont-mediated disruption of host cellular anatomical structure by PTOV1 expression — BREAST

Explore this box plot interactively →