PTOV1-AS1

Across TCGA pan-cancer cohorts, PTOV1-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated PTOV1-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher PTOV1-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PTOV1-AS1 expression acts as an unfavorable survival marker, although some lineages such as GBM and PAAD show a favorable association.

KIRC, MESO, and LIHC are the cancer types where PTOV1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	II,III,IV	0.379	0.639	<.001	92	view →
MESO	OS	Median	III,IV	0.437	0.667	.001	65	view →
LIHC	DFS	Quartile	All	0.442	0.638	<.001	60	view →
LGG	DFS	Median	All	0.634	0.844	<.001	52	view →
ACC	DFS	Tertile	All	0.302	0.692	.003	35	view →
LUSC	DFS	Quartile	II,III,IV	0.238	0.466	.020	21	view →
BLCA	DFS	Quartile	IV	0.221	0.620	.004	11	view →
GBM	DFS	Quartile	All	0.316	0.174	.009	9	view →
KICH	OS	Quartile	All	0.759	1.000	.008	8	view →
PRAD	DFS	Quartile	All	0.711	0.879	.025	8	view →
READ	DFS	Median	IV	0.179	0.936	.010	7	view →
SKCM	OS	Median	II,III,IV	0.790	0.899	.013	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

PTOV1-AS1–KIRC (DFS)

Open the KIRC breakdown →