PTMS

Across TCGA cell cohorts, PTMS RNA expression is significantly associated with the go_rna of many other GO terms, with 4,754 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PTMS-associated GO terms across cancer lineages are Trophectodermal cell differentiation, Protein depolymerization, and Plasmacytoid dendritic cell activation. Each is linked with PTMS in more than 10 cancer types. Because this analysis shows association rather than direction, both PTMS-to-partner and partner-to-PTMS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Trophectodermal cell differentiation grouped by PTMS-low versus PTMS-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PTMS→partner) and Y-score (partner→PTMS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Trophectodermal cell differentiation →	+0.113	+0.946	.001	.006	3	11
SKIN	Protein depolymerization →	+0.128	+1.255	<.001	<.001	3	11
LUNG_SCLC	Plasmacytoid dendritic cell activation →	-0.171	-1.470	.001	.003	3	11
URINARY_TRACT	Positive regulation of axon guidance →	+1.051	+1.515	.002	.001	3	10
STOMACH	Regulation of glycolytic process through fructose-6-phosphate →	+0.144	+1.826	<.001	<.001	3	10
STOMACH	Negative regulation of glycolytic process through fructose-6-phosphate →	+0.144	+1.826	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,754 associations by consensus.

Trophectodermal cell differentiation by PTMS expression — OVARY

Explore this box plot interactively →