PTMAP15

Across TCGA patient cohorts, PTMAP15 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,320 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PTMAP15-associated GO terms across cancer lineages are Regulation of DNA replication, Positive regulation of DNA metabolic process, and Regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Each is linked with PTMAP15 in more than 14 cancer types. Because this analysis shows association rather than direction, both PTMAP15-to-partner and partner-to-PTMAP15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA replication grouped by PTMAP15-low versus PTMAP15-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PTMAP15→partner) and Y-score (partner→PTMAP15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of DNA replication →	+0.064	+0.483	.001	<.001	2	15
ESCA	Positive regulation of DNA metabolic process →	+0.054	+0.401	.002	.002	3	14
KIRC	Regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.051	+0.174	<.001	<.001	3	12
KIRC	Peptidyl-lysine modification →	+0.038	+0.207	<.001	<.001	3	12
ESCA	Regulation of microtubule-based process →	+0.051	+0.577	<.001	<.001	3	12
ESCA	snRNA modification →	+0.052	+0.516	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,320 associations by consensus.

Regulation of DNA replication by PTMAP15 expression — ESCA

Explore this box plot interactively →