PTK2

Across TCGA patient cohorts, PTK2 protein abundance is significantly associated with the RNA expression of many other genes, with 12,322 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible PTK2-associated genes across cancer lineages are ZNF623, ZNF7, and WASHC5. Each is linked with PTK2 in more than 7 cancer types. Because this analysis shows association rather than direction, both PTK2-to-partner and partner-to-PTK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTK2 versus ZNF623 in LUAD, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTK2→partner) and Y-score (partner→PTK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ZNF623 →	+0.625	+0.450	<.001	<.001	3	8
LUAD	ZNF7 →	+0.590	+0.405	<.001	<.001	3	7
BRCA	WASHC5 →	+0.720	+0.302	<.001	.001	3	7
BRCA	ZNF16 →	+0.493	+0.351	<.001	<.001	3	7
LUAD	ZNF696 →	+0.700	+0.428	<.001	<.001	3	7
HNSC	ZNF250 →	+0.476	+0.290	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,322 associations by consensus.

PTK2 vs ZNF623 — LUAD

Explore this scatter interactively →