PTK2

Across TCGA cell cohorts, PTK2 RNA expression is significantly associated with the RNA expression of many other genes, with 11,248 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible PTK2-associated genes across cancer lineages are PHF20L1, ZC3H3, and ZNF7. Each is linked with PTK2 in more than 15 cancer types. Because this analysis shows association rather than direction, both PTK2-to-partner and partner-to-PTK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTK2 versus PHF20L1 in BONE, with a Pearson correlation of 0.59.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTK2→partner) and Y-score (partner→PTK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	PHF20L1 →	+1.052	+0.907	<.001	<.001	3	15
STOMACH	ZC3H3 →	+1.175	+1.382	<.001	<.001	3	15
BONE	ZNF7 →	+1.281	+1.383	<.001	<.001	3	15
LIVER	ZNF623 →	+1.080	+1.002	<.001	.003	2	16
STOMACH	HSF1 →	+1.366	+1.342	<.001	<.001	2	16
URINARY_TRACT	CHRAC1 →	+1.354	+1.181	<.001	<.001	2	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,248 associations by consensus.

PTK2 vs PHF20L1 — BONE

Explore this scatter interactively →