PTGS1

Across TCGA patient cohorts, PTGS1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,276 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PTGS1-associated genes across cancer lineages are STAC, IFFO1, and ADAM12. Each is linked with PTGS1 in more than 5 cancer types. Because this analysis shows association rather than direction, both PTGS1-to-partner and partner-to-PTGS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTGS1 versus STAC in GBM, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTGS1→partner) and Y-score (partner→PTGS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	STAC →	+1.813	+0.812	<.001	<.001	3	6
LSCC	IFFO1 →	+0.651	+0.458	<.001	<.001	3	6
CCRCC	ADAM12 →	+0.903	+0.495	.001	.003	3	6
BRCA	RAI2 →	+1.422	+0.329	<.001	.003	3	5
COAD	COLEC12 →	+1.042	+0.432	<.001	<.001	3	5
LSCC	CYTH4 →	+0.802	+0.459	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,276 associations by consensus.

PTGS1 vs STAC — GBM

Explore this scatter interactively →