PTGR2

Across TCGA patient cohorts, PTGR2 mutation is significantly associated with the RNA expression of many other genes, with 107 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PTGR2-associated genes across cancer lineages are RPL32P14, RNA5SP524, and OR5D2P. Each is linked with PTGR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PTGR2-to-partner and partner-to-PTGR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL32P14 grouped by PTGR2-low versus PTGR2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTGR2→partner) and Y-score (partner→PTGR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPL32P14 →	+0.088	+5.148	.007	.002	3	2
BLCA	RNA5SP524 →	+0.248	+7.640	<.001	.009	3	2
BLCA	OR5D2P →	+0.199	+7.640	<.001	.009	3	2
SKCM	OR5D14 →	+0.039	+7.816	<.001	.008	3	2
BLCA	LINC02647 →	+0.294	+7.640	<.001	.009	3	2
BRCA	RN7SL82P →	+0.128	+7.731	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 107 associations by consensus.

RPL32P14 by PTGR2 expression — UCEC

Explore this box plot interactively →