PTGR2

Across TCGA cell cohorts, PTGR2 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PTGR2-associated genes across cancer lineages are OR10W1, FTHL17, and S100G. Each is linked with PTGR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PTGR2-to-partner and partner-to-PTGR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10W1 grouped by PTGR2-low versus PTGR2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTGR2→partner) and Y-score (partner→PTGR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR10W1 →	+0.019	+4.977	<.001	.007	3	1
BLOOD_Lymphoma	FTHL17 →	+0.180	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	S100G →	+0.058	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	ODF4 →	+0.124	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	HELT →	+0.022	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	RNASE9 →	+0.015	+5.209	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

OR10W1 by PTGR2 expression — LARGE_INTESTINE

Explore this box plot interactively →