PTGR1

Across TCGA pan-cancer cohorts, PTGR1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated PTGR1 data layer compared with 21 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher PTGR1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated PTGR1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and PDAC show a favorable association.

CCRCC, GBM, and LUAD are the cancer types where PTGR1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	All	1.000	0.896	.006	26	view →
GBM	DFS	Tertile	All	0.478	0.857	.001	21	view →
LUAD	OS	Tertile	II,III,IV	0.431	0.864	.008	15	view →
PDAC	DFS	Tertile	III,IV	0.954	0.315	.002	12	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

PTGR1–CCRCC (OS)

Open the CCRCC breakdown →