PTGIS

Across TCGA patient cohorts, PTGIS RNA expression is significantly associated with the protein abundance of many other proteins, with 20,792 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PTGIS-associated proteins across cancer lineages are PRELP, DCN, and EFEMP2. Each is linked with PTGIS in more than 9 cancer types. Because this analysis shows association rather than direction, both PTGIS-to-partner and partner-to-PTGIS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTGIS versus PRELP in COAD, with a Pearson correlation of 0.64.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PTGIS→partner) and Y-score (partner→PTGIS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PRELP →	+0.992	+1.229	<.001	<.001	3	10
BRCA	DCN →	+1.048	+1.253	<.001	<.001	3	10
CCRCC	EFEMP2 →	+1.111	+2.144	<.001	<.001	3	10
OV	MMP2 →	+1.084	+1.636	<.001	<.001	3	10
BRCA	PODN →	+0.888	+1.059	<.001	<.001	3	9
PDAC	RARRES2 →	+0.756	+1.012	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,792 associations by consensus.

PTGIS vs PRELP — COAD

Explore this scatter interactively →